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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9118099318db144dd1386e1c81e5a6af1f6094b452db7196311cd4fc2d122de4' 
  AND token = 'BzeNLe8A/Y1GsnHnCg3mgUeDt6qFXQ2EFTvVu5ffGAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}