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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3b598a6f033268c194879652535a88047a38fb3af5f2148f6af2c4b70bc6a7' 
  AND token = 'FrdndrVE7yKX7+cTeq4PM28fywVjSAg/OWvrAm1xfAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}