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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46252ef02a64860ed0080602eb1c589eb4a4ac0172db81e1f83c5596569c0f16' 
  AND token = 'oBcut64v5lMD0mk7oDXnaVNk+Qy6YtNc9mUjnEActpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}