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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35cb687666593ebf4e9ee1f2c599db4074836ea59f5cfadc7a2179f5fafc217f' 
  AND token = 'hSdUh0CXZ0O/r7Viw5Pa7dDl+qtUVLXcJduiI0TRxrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}