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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9766af8417d35446e4e3ac710787a29747b46198b4f0481ca4744387b86f4f54' 
  AND token = 'csttqh/rEu6n+ZyVPZBdtzD8jpcRFBDsdpmd7NlRT9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}