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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df5fb71752c2b1d21602461f29dbb0cae6faabd5cc57f4d41d58f46ac78b60f' 
  AND token = 'StPItOilAo4cUpacP19MpV9Fotdm9ZUwe67fGwB8Nyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}