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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da4c21cb2923d718ee41e821cb132e1f0374a3e0edf2bbe7e89faa4c0f8c3e6' 
  AND token = 'TQBONrt5h2acQt5rLvXms2JrpBNqPB7QxbQis2IUyqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}