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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ab7190df4fe536cd625b30540b13eb80664047f8ed4ed7c00f1a4bac589fd7' 
  AND token = 'voUmL89NYKA+7Mhz8CxJWla9icgAF3xmdA//jrm8/0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}