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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b055d0997f18d00e9ae2bb3ade6a0fbd5a109500b04b78cebd071236734d20' 
  AND token = '5oV+vTcrHhBppWw/R5Kc9sr77KQaUs/5kmcYvj87K2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}