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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7572e48e9b04135e175e6c823508b553b4d712789904af40c1d4204263f5d8ce' 
  AND token = 'VP5rjwtcWOsM25eAVsw7jYFkdgknrcV3vxf+gphA2yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}