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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64c9e93afdb0e070151894c3e4caa32d601ed50914cb07266d2c716526a8fce' 
  AND token = 'F7XgxcZUcySJT4hzRbjQXltmmjWGNukHaONlAdNZCYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}