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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90bc82a878e3527f40c4046bb029f55c2993a0df0e128e60471e4a13c7c74ade' 
  AND token = 'eXe3S/KMAvxxq653pXYFiDFR8RpqZXRTG9y0dOGOHn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}