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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '502e66b9a69079d7da0a7c401408fb9840cb3e450187cf101fbf59d3b8f14dfb' 
  AND token = 'R0YIEwJmKNjjQU4OW6U8LdXugbhaO6YXZ56K5eUF3Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}