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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '790f68ec366f7ca849c26d8c90288d95c572d437bae3eb48de1d9dbe354b8c4d' 
  AND token = 'yYtwqpYAgdoIY2FouJaV4O2hPPu/IiNS6aY0kcHUDIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}