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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f783801ce86a4cd0bdd9573fa4258f8b737b060e7825c7c7d9cd593295ceb76' 
  AND token = '8FIFSIOXXsw8g5U5z/PZsQCM0rQiJI+HPzC9z8FN5O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}