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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07cd29f6ca75e4f85e2286e992f0c1ffeff732c936e038d601f359e04c4a8c00' 
  AND token = 'GU1Dzq5NfXk7nB8YRRn2bD/U1nsEu1pUxDh6reeU4uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}