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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd999fd3025e308390f1de5450309ac5e24c84e7802f86e31a507deb8850b6e' 
  AND token = '6xyapf8wEJfrL9LcYoU9GwwUmWKn63lwrFWhklmBk+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}