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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46619ace513c3b63797f782c20aa6d4be3c4c898a01ed23df7ddb6d10319737' 
  AND token = 'GopD87nqUfsMLL9Z947VHks5KHLjA+9eQ8nVn408b1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}