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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed086a18d3ee9ca57b9e7bda7ff969bee5631890dda4cdc24aac9c5026eba79' 
  AND token = 'XAXJZymna7TBGh0VEqIuGko/Iai/YZY1Oa+P+3RSUMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}