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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295bb0e50513015b2ad86ccb67a9649a732e133f922c1c82851cadaaa755726c' 
  AND token = 'w0wLM6f95/m1hhvN++2V7Nv4NL+PbonK805lNIv4GdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}