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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3e2bd7f2ce918b914e91818e7e6cadf65a69052d9e84c32be8e3053b273a4c' 
  AND token = 'FUyx20YCLs5qQhZPbMC7L1vm9QVSaqk6yuVjEQUB4jQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}