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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dcb321b9c7b53317d5b4c41dca7bb3a22775a231a73c3725db27b300a87ec9' 
  AND token = 'j9cnhLmGYI7Z+9l+yxjnlH4nNoDbP+FdB8lDmb1euHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}