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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5682f56471e82425f95b8e83cfc2a44cb561f41778017afb9c8871a806bf723' 
  AND token = 'eqch63MT8BPh+xH48d/SDcTVWhrBs06QMZtcBaRI684=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}