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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8844f960e7b1dfef633c3cc69964eeeaf547671345ce46100454ac3344569ca2' 
  AND token = 'irNEV2sDKgAD05JZ+5ND0Kmc2zSMEVB632AoAA2U1P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}