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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2b2356fb7cc173b091bf8a46a5d9815a06d8544c9c40b5071dde93fc02ec42' 
  AND token = 'AFv4IjZ6jGUNi1VqE+wRrEV9IJPuVp38sWkOZ7ycuC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}