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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa47dc68b7811ea4bf21575a1d6728353436d12f4c465bad486a4de8acf8f90' 
  AND token = 'fsxITzWIW/08DbMc80XgSQvCy4YKNVgbFvFlXkwlH9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}