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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca05433261e06a07e065b3093053e37cb97248e268564b53c08f6ad8f29c4e9c' 
  AND token = 'oCLEMrLKREzdWmbIK7XHYadtmk7/GW6GusDQJdeLkeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}