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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0005b75b4c1cda929c6744355ea439e700b920c6c7337c94c223ae86b9c540' 
  AND token = 'd7klfY7JQEuMyZkcCYQIlScCge1+CB9eCFDqjZRToRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}