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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb4efc3951df5f1fb371cd4cedf45d1547e3bba2da514d1719040696401dd16' 
  AND token = 'a66pJVza2HqZjz9x+WQXeJX1O3tL7zeluWQQrLw89i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}