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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002199105047ca744dae181e998b2b6e52864abdd650fede6c024b9eb6053da2' 
  AND token = '1pv/KhSVxdtbs9okJegfRAJD8eQdwYsJdOnSRDUg1RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}