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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fec4f3fcd618dba036d2a309c6b67fc581541fd62bf3512a8ce2abbbb400cf5' 
  AND token = 'SL8L8TjLVgtVjWbb8AyYFwKqmmPg80Hi62VZKmxDj3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}