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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e4218c39aa2374905c136af8c03b811fa59876dee27a14f24619ea735a991c' 
  AND token = '8d+9dHp//I5mIGPxoeOT/G3SAvi/oBlCNFpHe0/Pueg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}