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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42849195c140dd104889b39ff4a1d192030469792b0308659e4ab4b8a5ce544' 
  AND token = 'XOQrbVhx+iyYgrO9ZX6kokjGoly/8+NR6t1/0hrxjck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}