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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d7cd53893c3b95d2dbee0db3296828d67a213f5c6a3fc6f3ecbc45891a8c70' 
  AND token = 'fDXS83Asv8V49Itmmr2u0KHtpfu0SdFs+oAmAbTmTxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}