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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2725d6a3ea398f71321c7bf2f967a469cfdb443c11646e5a463c8a6a6e0a7f7' 
  AND token = 'S1mPWIZTdnzgEsHAyHqFXoTISPEFaq65rpt7zS8Uu/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}