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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fda6e7b45a494165cbe8828e8df8e4e72ed933e2ab0ecb0b6a3acf6524f9be5' 
  AND token = 'yPnn6QJsfPZoy001Qpo+YMz7MRFxe0U3BYQkkcXFbz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}