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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f2adb23b52970a3b5ab0fbc22bd31e27b266d1bfb868bf806fb5dc2afebc27c' 
  AND token = 'sal8I2uQLlGMMxBifDl2bXXCI6bRrw1qBktKiO86OCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}