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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424a770ce14754bfb95b6f08a80cf63e357a5c407a50735603a6dbf8b2e6cd8b' 
  AND token = 'krgEWJm2Ti0DZWQ/i4/F0JlDfQzpHYkV23MOiIDn3Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}