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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d99a49b7e6ddd463e6f43e35adefcb939b2acd4b084c43330c1129af25bd195' 
  AND token = 'CgbmGAs5FRoOxfV9pRhsCSlXd6WImu0XftpmA3G5Ze0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}