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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e33ff4dbac765a0056f1ba9fcc8041ef4391f71e0d2bf7e250f129460d118ba' 
  AND token = '9N0SdoJseELO4VKMea8vS3ZuDC+njHrUT5SdVmqRuXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}