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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df9919d071aaa25637262656bf0b043b1d399c8cfdd95c3f0d6eb19a8bc560c8' 
  AND token = 'iiMhKrjyq6X6tsX7AB2NGicpdr/5mCsWDpMNdZzrzT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}