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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de03ef787c36b0e1d4df6af71c03df1c32a4e000cf0b54df1354e4e962578436' 
  AND token = '/BYltcIzI7x7mziByBWn0Iu1zPm6BIjeWaYffiAn2JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}