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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48ef095fb92d25adbf30d6241ada761e71791af3e137465b00388e91f5399e9' 
  AND token = 'qWc+B7GqUFQdWpAGpzkxdHSHB+a75HjoVA1XdngUp2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}