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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a2739017c8d0ed454951a543b90c66fbd0b1a56b1a7f0ee8a91b57563efcd0' 
  AND token = 'B0Ly8wNQDooHhBh73F6lm227bAnBhhdejMo78cqrfAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}