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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a76b2b1ee6ec8601d5c707e43eee380f5452c0fb0dc2b13a0a7c98f26ac357' 
  AND token = 'wACS9G23bZagc3TV6C05IL2Y0g+8DMsrwUZCArrrdmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}