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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b6e5ef8d551033776f2eddb17c99887237a4a9410ae895706ee85540af26ac' 
  AND token = 'U3WtKxDoi4XFkac1HLLO7PguFVQ/FgQID8MDFWTFlAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}