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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a18bd216db1a78cb30f093e0e31676f94a604b77304b03d3dbb9dfe5e21270' 
  AND token = 'DJFciSfOHuS39q85xer4ZtqgVScODNIFaxrkM72HMlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}