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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203a2d6377369ba4e8fb211ca33c61c993c48d3b0bed19d2f4b02db25c3408df' 
  AND token = 'qxy/IpygNqn43Ur1jVGBNWz3AYg8pFudsAlyNsIvZ4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}