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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0e4a4659358d6cb3e4960520546e6bb6cd5efcda3f70f13bfadeb3171a2f91' 
  AND token = 'EkRBp7avto8cP8B/dEuaojTOhhnuwNEtamdIKfQy3nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}