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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cda3580daf3867dc3d1080cbd8e584d7e127baac034572ab1562b3003ee2f8d' 
  AND token = 'En19onkrz//pSP4kgKdfPDBthbQuCqTqa7cCFIXMmD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}